Research Project Portals

SPBU on web site published an article about achievement of the Center and published article.

New article on Genome Russia project accepted to publication

Daria V. Zhernakova, Vladimir Brukhin, Sergey Malov, Taras K. Oleksyk, Klaus Peter Koepfli, Anna Zhuk, Pavel Dobrynin, Sergei Kliver, Nikolay Cherkasov, Gaik Tamazian, Mikhail Rotkevich, Ksenia Krasheninnikova, Igor Evsyukov, Sviatoslav Sidorov, Anna Gorbunova, Ekaterina Chernyaeva, Andrey Shevchenko, Sofia Kolchanova, Alexei Komissarov, Serguei Simonov, Alexey Antonik, Anton Logachev, Dmitrii E. Polev, Olga A. Pavlova, Andrey S. Glotov, Vladimir Ulantsev, Ekaterina Noskova, Tatyana K. Davydova, Tatyana M. Sivtseva, Svetlana Limborska, Oleg Balanovsky, Vladimir Osakovsky, Alexey Novozhilov, Valery Puzyrev, Stephen J. O'Brien,
Genome-wide sequence analyses of ethnic populations across Russia,
Genomics, 2019,
 
ISSN 0888-7543,
https://doi.org/10.1016/j.ygeno.2019.03.007.
(http://www.sciencedirect.com/science/article/pii/S0888754318307419)
Abstract: The Russian Federation is the largest and one of the most ethnically diverse countries in the world, however no centralized reference database of genetic variation exists to date. Such data are crucial for medical genetics and essential for studying population history. The Genome Russia Project aims at filling this gap by performing whole genome sequencing and analysis of peoples of the Russian Federation. Here we report the characterization of genome-wide variation of 264 healthy adults, including 60 newly sequenced samples. People of Russia carry known and novel genetic variants of adaptive, clinical and functional consequence that in many cases show allele frequency divergence from neighboring populations. Population genetics analyses revealed six phylogeographic partitions among indigenous ethnicities corresponding to their geographic locales. This study presents a characterization of population-specific genomic variation in Russia with results important for medical genetics and for understanding the dynamic population history of the world's largest country.

Every Monday at 3pm we have a staff meeting to discuss current projects and other topics.

Theodosius Dobzhansky

Geneticist & Evolutionary Biologist
 
Theodosius Dobzhansky American geneticist and evolutionary biologist and a central figure in the field of evolutionary biology is recognized for...

Heads of the Center

Anastasia Samsonova

Professor, Head of the Centre

Publications


Alexander Kanapin

Professor, co-Head of the Centre

Publications

Stephen J O'Brien

Chief Scientific Officer
 
I welcome you to the Site of the brand new Center of Genome Informatics at St Petersburg State University. The...

Lab's news

SPBU on web site published an article about achievement of the Center and published article.

September, 27 2019 ( Friday at 2pm: Dr. Kirill Vinnikov from Hawaii University (USA) and head of the lab at the Far Eastern Federal University (Vladivostok) "Exome sequencing of non-model species"