Ekaterina Chernyaeva

Position:
echernyaeva

Ekaterina is a postdoctoral fellow at the Theodosius Dobzhansky Center for Genome Informatics. Ekaterina has graduated from the St.Petersburg State University with aPh.D. in Biology (Biochemistry) in March 2012. Her Ph.D. thesis was devoted to molecular-biological study of Mycobacterium tuberculosis strains spread in St. Petersburg in different patient-groups and analysis of point mutations associated with drug resistance. She started her research work as a student of the University studying genetic diversity of HIV-1 isolates obtained among injecting drug users living in St. Petersburg. This work has been performed within bounds of the Russian HIV/AIDS vaccine development project. In 2006-2007 she attended Advanced Tuberculosis Laboratory Training (Wadsworth Center, New York State Department of Health, USA) funded by Fogarty International Center, NIH. After return to Russia she started to study M. tuberculosis complex strains spread in St. Petersburg and Leningrad region. Her scientific interests lie in the field of molecular biology of human pathogens and human genetic markers associated with infectious diseases.

List of publications

  1. Chernyaeva E, Dobrynin P, Pestova N, Matveeva N, Zhemkov V, Kozlov A. Molecular genetic analysis of Mycobacterium tuberculosis strains spread in different patient groups in St. Petersburg, Russia. Eur J Clin Microbiol Infect Dis. 2012 Aug;31(8):1753-7. doi: 10.1007/s10096-011-1497-2. Epub 2011 Dec 8. PubMed PMID: 22160887.
  2. Chernyaeva E, Fedorova E, Zhemkova G, Korneev Y, Kozlov A. Characterization of multiple and extensively drug resistant Mycobacterium tuberculosis isolates with different ofloxacin-resistance levels. Tuberculosis (Edinb). 2013 May;93(3):291-5. doi: 10.1016/j.tube.2013.02.005. Epub 2013 Mar 13. PubMed PMID: 23491718.
  3. Chernyaeva EN, Shulgina MV, Rotkevich MS, Dobrynin PV, Simonov SA, Shitikov EA, Ischenko DS, Karpova IY, Kostryukova ES, Ilina EN, Govorun VM, Zhuravlev VY, Manicheva OA, Yablonsky PK, Isaeva YD, Nosova EY, Mokrousov IV, Vyazovaya AA, Narvskaya OV, Lapidus AL, O’Brien SJ. Genome-wide Mycobacterium tuberculosis variation (GMTV) database: a new tool for integrating sequence variations and epidemiology. BMC Genomics. 2014 Apr 25;15:308. doi: 10.1186/1471-2164-15-308. PubMed PMID: 24767249; PubMed Central PMCID: PMC4234438.
  4. Zimenkov DV, Kulagina EV, Antonova OV, Krasnova MA, Chernyaeva EN, Zhuravlev VY, Kuz’min AV, Popov SA, Zasedatelev AS, Gryadunov DA. Evaluation of a low-density hydrogel microarray technique for mycobacterial species identification. J Clin Microbiol. 2015 Apr;53(4):1103-14. doi: 10.1128/JCM.02579-14. Epub 2015 Jan 21. PubMed PMID: 25609722; PubMed Central PMCID: PMC4365248.
  5. Acosta F, Chernyaeva E, Mendoza L, Sambrano D, Correa R, Rotkevich M, Tarté M, Hernández H, Velazco B, de Escobar C, de Waard JH, Goodridge A. Mycobacterium bovis in Panama, 2013. Emerg Infect Dis. 2015 Jun;21(6). doi: 10.3201/eid2106.141821. PubMed PMID: 25988479.
  6. Velichko N, Chernyaeva E, Averina S, Gavrilova O, Lapidus A, Pinevich A. Consortium of the ‘bichlorophyllous’ cyanobacterium Prochlorothrix hollandica and chemoheterotrophic partner bacteria: culture and metagenome based description. Environ Microbiol Rep. 2015 May 20. doi: 10.1111/1758-2229.12298. [Epub ahead of print] PubMed PMID: 25990300.
  7. И. В. Духовлинов, Е. А. Федорова, Е. Г. Богомолова, О. А. Добровольская, Е. Н. Черняева, Р. И. Аль-Шехадат, А. С. Симбирцев. ПОЛУЧЕНИЕ РЕКОМБИНАНТНОГО БЕЛКА CRM197 В КЛЕТКАХ E. COLI. Инфекция и иммунитет 2015, Т. 5, No 1, с. 37–44
    DOI: http://dx.doi.org/10.15789/2220-7619-2015-1-37-44
  8. Trends in molecular epidemiology of drug-resistant tuberculosis in Republic of Karelia, Russian Federation
    Igor Mokrousov, Anna Vyazovaya, Natalia Solovieva, Tatiana Sunchalina, Yuri Markelov, Ekaterina Chernyaeva, Natalia Melnikova, Marine Dogonadze, Daria Starkova, Neliya Vasilieva, Alena Gerasimova, Yulia Kononenko, Viacheslav Zhuravlev, Olga Narvskaya
    BMC Microbiol. 2015; 15: 279. Published online 2015 December 18. doi: 10.1186/s12866-015-0613-3
    PMCID: PMC4683759
  9. Suvorov A, Dukhovlinov I, Leontieva G, Kramskaya T, Koroleva I, Grabovskaya K, Fedorova E, Chernyaeva E, Klimov N, Orlov A and Uversky V
    Chimeric Protein PSPF, a Potential Vaccine for Prevention Streptococcus pneumoniae Infection
    J Vaccines Vaccin 6:304. doi:10.4172/2157-7560.1000304
  10. Chernyaeva E. Biochemical mechanisms of Mycobacterium tuberculosis drug resistance // Vestnik St. Petersburg University. Ser. 3. 2012. Issue 2. P. 77–91.
  11. Chernyaeva E, Dobrynin P, Pestova N, Matveeva N, Zhemkov V, Kozlov. A. / Evaluation of mutations in gyrA and gyrB genes associated with ofloxacin-resistance and molecular-genetic characteristic of ofloxacin-resistant M. tuberculosis isolates revealed in St. Petersburg in 2008. // Vestnik St. Petersburg University, 2010. Series 3, V.4. P. 117-125
  12. E. Chernyaeva, A. Masharsky, S. Verevochkin, S. Gagarina, N. Klimov, A. Kozlov / Genetic Diversity of HIV-1 isolates Spread Among Injecting Drug Users in St. Petersburg // Physiology and Pathology of Immune System, 2007. V.11, №2, P. 9-14.